Current COVID-19 vaccine studies
The UK is a leading force in the development of vaccines for COVID-19. Search our database of studies and trials currently under way.
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Project name
Lead Institution
Summary
Funders
Imperial College London
The MELODY study is using home antibody testing to improve our understanding of responses to COVID-19 vaccination in individuals who are receiving immunosuppression.
Medical Research Council, Kidney Research UK, Vasculitis UK, Blood Cancer UK, Systic Fibrosis Trust.
Queen Mary University of London
COVIDENCE UK is a population-based longitudinal study to determine potential risk factors for COVID-19 and determinants of vaccine immunogenicity.
Barts Charity, Pharma Nord Ltd, the Fischer Family Trust, Dangoor Education, DSM Nutritional Products Ltd, the Karl R Pfleger Foundation, the AIM Foundation, Synergy Biologics Ltd, Thornton & Ross Ltd, Warburtons Ltd, Mr Matthew Isaacs (personal donation), and Hyphens Pharma Ltd.
Queen Mary University of London
CORONAVIT is a randomised controlled trial of 6200 people to evaluate the impact of vitamin D replacement on incidence and severity of COVID-19, including whether vitamin D influences vaccine-induced host responses to SARS-CoV-2.
Barts Charity, Pharma Nord Ltd, the Fischer Family Trust, Dangoor Education, DSM Nutritional Products Ltd, the Karl R Pfleger Foundation, the AIM Foundation, Synergy Biologics Ltd, Thornton & Ross Ltd, Warburtons Ltd, Mr Matthew Isaacs (personal donation), and Hyphens Pharma Ltd.
UCL
This study will establish the strength and durability of COVID-19 vaccine responses in people with two conditions that weaken the immune system: HIV and B cell lymphoma, a cancer of immune cells.
Medical Research Council, UK Research and Innovation, Blood Cancer UK, NIHR UCLH Biomedical Research Centre
University of Oxford
This research aims to study people’s response to SARS-COV-2 vaccines by looking at how a person’s genes are related to their immune response to the vaccine.
Medical Research Council
Understanding Mechanisms of Thrombosis and Thrombocytopenia in COVID-19 and with SARS-CoV-2 Vaccines
University of Liverpool
The aim of this study is to discover why COVID-19 vaccines can lead to thrombotic thrombocytopenia syndrome in rare cases.
National Institute for Health Research
University of Birmingham
By recruiting 1050 patients with antibody deficiency, this multicentre study will aim to answer important questions about the immune response to COVID-19 infection in individuals with immune deficiency and provide insight into whether vaccination will offer effective protection from the disease in the future.
UK Research and Innovation
University of Leicester
We are investigating the impact of ethnicity on the outcomes from COVID-19 in a group of healthcare workers across the UK.
The National Core Studies Programme
The University of Nottingham
A multi-centre randomised controlled trial examining the effects of temporarily suspending low-dose methotrexate treatment for two weeks after SARS-CoV-2 vaccine booster on vaccine response in immunosuppressed adults with inflammatory condition.
National Institute for Health Research (NIHR) Efficacy and Mechanism Evaluation (EME) programme
The University of Nottingham
The aim of the Vasculitis study is to examine the immune responses to vaccination in individuals with vasculitis compared to age-matched healthy controls.
Vasculitis UK