Current COVID-19 vaccine studies
The UK is a leading force in the development of vaccines for COVID-19. Search our database of studies and trials currently under way.
The Vaccine Booster Breakthroughs project (VBB) builds upon the successful, innovative work of the earlier Vaccine Breakthroughs Project.
The Vaccine Breakthroughs project investigated serious COVID-19 ‘breakthrough’ events (i.e. hospitalisation and death) that occurred after a person received their primary and third / first booster dose vaccinations. This work provided crucial results which identified which groups of people are more at risk of experiencing these serious outcomes. These results were relayed to the Joint Commitee of Vaccination and Immunisation to help inform the strategy for the Autumn 2022 booster vaccine roll-out.
Now, VBB will help to work out the groups of people who are most at risk of experiencing a serious breakthrough event after their Autumn 2022 / second booster dose vaccination. More specifically, VBB aims to determine:
The VBB team will first conduct individual analyses in England, Northern Ireland, Scotland and Wales, then pool the results together for a UK-wide analysis. They will do this by safely accessing data from Royal College of General Practitioners' ORCHID national surveillance dataset (England); the Honest Broker Service (Northern Ireland); the EAVE II project (Scotland); and the SAIL Databank (Wales).
UK Research and Innovation (as part of the COVID-19 National Core Studies)