PETReA: a phase 3 trial testing whether PET scans can help make treatment decisions for people with follicular lymphoma

Project summary:

The aim of this trial is to find out if PET scans can be helpful in deciding whether people with follicular lymphoma need maintenance treatment after first-line treatment. It also aims to find out:

  • if rituximab maintenance can be avoided for people with a good response to first-line treatment, preventing unnecessary side effects. 
  • if adding lenalidomide to rituximab maintenance can improve outcomes for people who have residual (leftover) lymphoma after first-line treatment.

A sub-study of the PETReA trial is looking at how effective COVID-19 vaccination is for people with follicular lymphoma.

Leader researcher:

Professor Andrew Pettitt

Lead institution:

University of Liverpool