The OCTAVE trial

Project summary:

The OCTAVE trial is a multi-centre, multi-disease, prospective observational cohort trial to investigate the effectiveness of COVID-19 vaccines in clinically at-risk patient groups. The researchers will build on years of experience in understanding the immune system in the context of chronic conditions. OCTAVE will help inform how best to vaccinate patients with chronic conditions, and protect them from COVID-19 infection in the future.


National Institute for Health Research (NIHR), UK Research and Innovation (UKRI)

Leader researcher:

Professor Iain McInnes

Lead institution:

University of Glasgow

Vaccine type:


Recruitment for clinical trial open: