CIA: 80s VR (Coronavirus Immunology Analysis study: Over 80s vaccination response)

Project summary:

This study aims to understand, at a qualitative and quantitative level, immune response durability in 'real-life settings' of different vaccination regimens for individuals who are over 80 years of age living in the community in the UK. To achieve this, we will track longitudinal immunity, analysing serum antibody titre and  live virus neutralisation, both to wild-type and variant targets. In terms of T cell immunity, we will track durability of response and  frequency to wild-type and variant epitopes using a range of approaches.


The National Core Studies Programme (NCS) immunity

Leader researcher:

Professor Paul Moss

Lead institution:

University of Birmingham

Vaccine type: