SARS-CoV-2 vaccine ResPonse In Obesity (SCORPIO)

Project summary:

This study will investigate the effect of obesity on COVID-19 vaccine effectiveness, as part of existing weight loss programmes in the obesity clinic in Cambridge University Hospital NHS Trust and King's College London.
 
Researchers will also perform a meta-analysis of 50,000 people from existing UK studies to investigate the link between BMI and vaccine responses across the full range from overweight, to obese and severely obese. By doing this, the researchers aim to identify nutritional and metabolomic biomarkers that are linked with vaccine responses and test whether weight loss can improve vaccine responses in obese people.

Funders

UK Research and Innovation

Leader researcher:

Professor Sadaf Farooqi

Lead institution:

University of Cambridge